Haiyan Huang is a professor in the Department of Statistics at the University of California, Berkeley. They are also the Director for the Center for Computational Biology. Their research areas are in Computational Biology and Applied Statistics. They are interested in solving practical problems in emerging bio data-intensive systems, and in understanding and developing theoretical principles of the practical methods. Current focuses are: 1) develop statistical methods that provide a consistent formulation between the statistical modeling and the biological nature of data, 2) understand and solve the problem of unreliable estimates in analyzing high dimensional structured data, and 3) tackle the challenges posed by the high level of noise and the lack of reproducibility in the datasets from different resources.